Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer

Epigenetic silencing of tumor suppressor genes (TSGs) through DNA methylation and histone changes is a main hallmark of cancer. Ubiquitin-like with PHD and RING Finger domains 1 (UHRF1) is a potent oncogene overexpressed in various solid and haematological tumors and its high expression levels are a...

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Detalles Bibliográficos
Autores principales: Alhosin, Mahmoud, Omran, Ziad, Zamzami, Mazin A., Al-Malki, Abdulrahman L., Choudhry, Hani, Mousli, Marc, Bronner, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108085/
https://www.ncbi.nlm.nih.gov/pubmed/27839516
http://dx.doi.org/10.1186/s13046-016-0453-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108085/
https://www.ncbi.nlm.nih.gov/pubmed/27839516
http://dx.doi.org/10.1186/s13046-016-0453-5

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