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Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer

Epigenetic silencing of tumor suppressor genes (TSGs) through DNA methylation and histone changes is a main hallmark of cancer. Ubiquitin-like with PHD and RING Finger domains 1 (UHRF1) is a potent oncogene overexpressed in various solid and haematological tumors and its high expression levels are a...

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Detalles Bibliográficos
Autores principales:	Alhosin, Mahmoud, Omran, Ziad, Zamzami, Mazin A., Al-Malki, Abdulrahman L., Choudhry, Hani, Mousli, Marc, Bronner, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108085/ https://www.ncbi.nlm.nih.gov/pubmed/27839516 http://dx.doi.org/10.1186/s13046-016-0453-5

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