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Chronic exposure to haloperidol and olanzapine leads to common and divergent shape changes in the rat hippocampus in the absence of grey-matter volume loss

BACKGROUND: One of the most consistently reported brain abnormalities in schizophrenia (SCZ) is decreased volume and shape deformation of the hippocampus. However, the potential contribution of chronic antipsychotic medication exposure to these phenomena remains unclear. METHOD: We examined the effe...

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Detalles Bibliográficos
Autores principales: Crum, W. R., Danckaers, F., Huysmans, T., Cotel, M.-C., Natesan, S., Modo, M. M., Sijbers, J., Williams, S. C. R., Kapur, S., Vernon, A. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108303/
https://www.ncbi.nlm.nih.gov/pubmed/27516217
http://dx.doi.org/10.1017/S0033291716001768