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Luteolin-7-glucoside inhibits IL-22/STAT3 pathway, reducing proliferation, acanthosis, and inflammation in keratinocytes and in mouse psoriatic model

The epidermis is a dynamic tissue in which keratinocytes proliferate in the basal layer and undergo a tightly controlled differentiation while moving into the suprabasal layers. The balance between keratinocyte proliferation, differentiation, and death is essential, and its perturbation can result i...

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Detalles Bibliográficos
Autores principales: Palombo, R, Savini, I, Avigliano, L, Madonna, S, Cavani, A, Albanesi, C, Mauriello, A, Melino, G, Terrinoni, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108310/
https://www.ncbi.nlm.nih.gov/pubmed/27537526
http://dx.doi.org/10.1038/cddis.2016.201