Glucolipotoxicity initiates pancreatic β-cell death through TNFR5/CD40-mediated STAT1 and NF-κB activation

Type 2 diabetes is a chronic metabolic disorder, where failure to maintain normal glucose homoeostasis is associated with, and exacerbated by, obesity and the concomitant-elevated free fatty acid concentrations typically found in these patients. Hyperglycaemia and hyperlipidaemia together contribute...

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Detaylı Bibliyografya
Asıl Yazarlar: Bagnati, Marta, Ogunkolade, Babatunji W, Marshall, Catriona, Tucci, Carmen, Hanna, Katie, Jones, Tania A, Bugliani, Marco, Nedjai, Belinda, Caton, Paul W, Kieswich, Julius, Yaqoob, Muhammed M, Ball, Graham R, Marchetti, Piero, Hitman, Graham A, Turner, Mark D
Materyal Türü: Online Makale Metin
Dil:English
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Original Article
Online Erişim:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108311/
https://www.ncbi.nlm.nih.gov/pubmed/27512950
http://dx.doi.org/10.1038/cddis.2016.203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108311/
https://www.ncbi.nlm.nih.gov/pubmed/27512950
http://dx.doi.org/10.1038/cddis.2016.203

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