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KDM5A controls bone morphogenic protein 2-induced osteogenic differentiation of bone mesenchymal stem cells during osteoporosis

Bone morphogenetic protein 2 (BMP2) has been used to induce bone regeneration by promoting osteogenic differentiation of bone marrow-derived mesenchymal stem cells (MSCs). However, its effect is attenuated in osteoporotic conditions by unknown mechanisms. In this study, we investigated the molecular...

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Detalles Bibliográficos
Autores principales: Wang, Chuandong, Wang, Jing, Li, Jiao, Hu, Guoli, Shan, Shengzhou, Li, Qingfeng, Zhang, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108323/
https://www.ncbi.nlm.nih.gov/pubmed/27512956
http://dx.doi.org/10.1038/cddis.2016.238