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Anti-apoptotic Bcl-X(L) but not Mcl-1 contributes to protection against virus-induced apoptosis

Infection of mammalian cells with viruses often induces apoptosis. How the recognition of viruses leads to apoptosis of the infected cell and which host cell factors regulate this cell death is incompletely understood. In this study, we focussed on two major anti-apoptotic proteins of the host cell,...

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Detalles Bibliográficos
Autores principales: Ohmer, Michaela, Weber, Arnim, Sutter, Gerd, Ehrhardt, Katrin, Zimmermann, Albert, Häcker, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108327/
https://www.ncbi.nlm.nih.gov/pubmed/27537523
http://dx.doi.org/10.1038/cddis.2016.242