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Fucosylation of LAMP-1 and LAMP-2 by FUT1 correlates with lysosomal positioning and autophagic flux of breast cancer cells

Alpha1,2-fucosyltransferases, FUT1 and FUT2, which transfer fucoses onto the terminal galactose of N-acetyl-lactosamine via α1,2-linkage have been shown to be highly expressed in various types of cancers. A few studies have shown the involvement of FUT1 substrates in tumor cell proliferation and mig...

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Detalles Bibliográficos
Autores principales: Tan, Keng-Poo, Ho, Ming-Yi, Cho, Huan-Chieh, Yu, John, Hung, Jung-Tung, Yu, Alice Lin-Tsing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108328/
https://www.ncbi.nlm.nih.gov/pubmed/27560716
http://dx.doi.org/10.1038/cddis.2016.243