Notch-Hes-1 axis controls TLR7-mediated autophagic death of macrophage via induction of P62 in mice with lupus

The increased death of macrophages has been considered as a pathogenic factor for systemic lupus erythematosus (SLE), and dysfunction of autophagy may contribute to improper cell death. However, the effect of autophagy on macrophage during the pathogenesis of SLE is still unclear. Here we found that...

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Detalles Bibliográficos
Autores principales: Li, Xiaojing, Liu, Fei, Zhang, Xuefang, Shi, Guoping, Ren, Jing, Ji, Jianjian, Ding, Liang, Fan, Hongye, Dou, Huan, Hou, Yayi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108329/
https://www.ncbi.nlm.nih.gov/pubmed/27537524
http://dx.doi.org/10.1038/cddis.2016.244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108329/
https://www.ncbi.nlm.nih.gov/pubmed/27537524
http://dx.doi.org/10.1038/cddis.2016.244

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