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Transferrin receptor facilitates TGF-β and BMP signaling activation to control craniofacial morphogenesis
The Pierre Robin Sequence (PRS), consisting of cleft palate, glossoptosis and micrognathia, is a common human birth defect. However, how this abnormality occurs remains largely unknown. Here we report that neural crest cell (NCC)-specific knockout of transferrin receptor (Tfrc), a well known transfe...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108332/ https://www.ncbi.nlm.nih.gov/pubmed/27362800 http://dx.doi.org/10.1038/cddis.2016.170 |