AKT activation controls cell survival in response to HDAC6 inhibition

HDAC6 is emerging as an important therapeutic target for cancer. We investigated mechanisms responsible for survival of tumor cells treated with a HDAC6 inhibitor. Expression of the 20 000 genes examined did not change following HDAC6 treatment in vivo. We found that HDAC6 inhibition led to an incre...

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Detalles Bibliográficos
Autores principales: Kaliszczak, M, Trousil, S, Ali, T, Aboagye, E O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108334/
https://www.ncbi.nlm.nih.gov/pubmed/27362804
http://dx.doi.org/10.1038/cddis.2016.180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108334/
https://www.ncbi.nlm.nih.gov/pubmed/27362804
http://dx.doi.org/10.1038/cddis.2016.180

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