A HIF-1α-driven feed-forward loop augments HIF signalling in Hep3B cells by upregulation of ARNT

Oxygen-deprived (hypoxic) areas are commonly found within neoplasms caused by excessive cell proliferation. The transcription factor Aryl hydrocarbon receptor nuclear translocator (ARNT) is part of the hypoxia-inducible factor (HIF) pathway, which mediates adaptive responses to ensure cellular survi...

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Detalles Bibliográficos
Autores principales: Mandl, M, Lieberum, M-K, Depping, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108338/
https://www.ncbi.nlm.nih.gov/pubmed/27362802
http://dx.doi.org/10.1038/cddis.2016.187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108338/
https://www.ncbi.nlm.nih.gov/pubmed/27362802
http://dx.doi.org/10.1038/cddis.2016.187

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