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A HIF-1α-driven feed-forward loop augments HIF signalling in Hep3B cells by upregulation of ARNT
Oxygen-deprived (hypoxic) areas are commonly found within neoplasms caused by excessive cell proliferation. The transcription factor Aryl hydrocarbon receptor nuclear translocator (ARNT) is part of the hypoxia-inducible factor (HIF) pathway, which mediates adaptive responses to ensure cellular survi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108338/ https://www.ncbi.nlm.nih.gov/pubmed/27362802 http://dx.doi.org/10.1038/cddis.2016.187 |