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Does murine spermatogenesis require WNT signalling? A lesson from Gpr177 conditional knockout mouse models

Wingless-related MMTV integration site (WNT) proteins and several other components of the WNT signalling pathway are expressed in the murine testes. However, mice mutant for WNT signalling effector β-catenin using different Cre drivers have phenotypes that are inconsistent with each other. The compl...

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Detalles Bibliográficos
Autores principales: Chen, Su-Ren, Tang, J-X, Cheng, J-M, Hao, X-X, Wang, Y-Q, Wang, X-X, Liu, Y-X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108341/
https://www.ncbi.nlm.nih.gov/pubmed/27362799
http://dx.doi.org/10.1038/cddis.2016.191