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Perdeuteration, crystallization, data collection and comparison of five neutron diffraction data sets of complexes of human galectin-3C

Galectin-3 is an important protein in molecular signalling events involving carbohydrate recognition, and an understanding of the hydrogen-bonding patterns in the carbohydrate-binding site of its C-terminal domain (galectin-3C) is important for the development of new potent inhibitors. The authors a...

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Detalles Bibliográficos
Autores principales: Manzoni, Francesco, Saraboji, Kadhirvel, Sprenger, Janina, Kumar, Rohit, Noresson, Ann-Louise, Nilsson, Ulf J., Leffler, Hakon, Fisher, S. Zoë, Schrader, Tobias E., Ostermann, Andreas, Coates, Leighton, Blakeley, Matthew P., Oksanen, Esko, Logan, Derek T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108347/
https://www.ncbi.nlm.nih.gov/pubmed/27841752
http://dx.doi.org/10.1107/S2059798316015540