Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase

Fructose-1,6-bisphosphatase (FBPase) is a key regulator of gluconeogenesis and a potential drug target for type 2 diabetes. FBPase is a homotetramer of 222 symmetry with a major and a minor dimer interface. The dimers connected via the minor interface can rotate with respect to each other, leading t...

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Detalles Bibliográficos
Autores principales: Ruf, Armin, Tetaz, Tim, Schott, Brigitte, Joseph, Catherine, Rudolph, Markus G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2016
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108348/
https://www.ncbi.nlm.nih.gov/pubmed/27841754
http://dx.doi.org/10.1107/S2059798316016715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108348/
https://www.ncbi.nlm.nih.gov/pubmed/27841754
http://dx.doi.org/10.1107/S2059798316016715

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