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Platelet Integrin αIIbβ3 Inhibitor Rescues Progression of Apoptosis in Human Platelets

BACKGROUND: Apoptosis plays an important role in the physiology of platelet function. We aimed to detect the effect of the platelet integrin αIIbβ3 inhibitor, tirofiban, on apoptotic events, including mitochondrial inner-membrane potential (ΔΨm), phosphatidylserine (PS) exposure on platelet surface,...

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Detalles Bibliográficos
Autores principales: Zhu, Jie, Wang, Qinghang, Nie, Yumei, Yan, Rong, Dai, Kesheng, Zhou, Birong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108368/
https://www.ncbi.nlm.nih.gov/pubmed/27827357
http://dx.doi.org/10.12659/MSM.900820