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Identifying significant gene‐environment interactions using a combination of screening testing and hierarchical false discovery rate control

Although gene‐environment (G× E) interactions play an important role in many biological systems, detecting these interactions within genome‐wide data can be challenging due to the loss in statistical power incurred by multiple hypothesis correction. To address the challenge of poor power and the lim...

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Detalles Bibliográficos
Autores principales: Frost, H. Robert, Shen, Li, Saykin, Andrew J., Williams, Scott M., Moore, Jason H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108431/
https://www.ncbi.nlm.nih.gov/pubmed/27578615
http://dx.doi.org/10.1002/gepi.21997