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Identifying significant gene‐environment interactions using a combination of screening testing and hierarchical false discovery rate control
Although gene‐environment (G× E) interactions play an important role in many biological systems, detecting these interactions within genome‐wide data can be challenging due to the loss in statistical power incurred by multiple hypothesis correction. To address the challenge of poor power and the lim...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108431/ https://www.ncbi.nlm.nih.gov/pubmed/27578615 http://dx.doi.org/10.1002/gepi.21997 |