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Are aberrant phase transitions a driver of cellular aging?

Why do cells age? Recent advances show that the cytoplasm is organized into many membrane‐less compartments via a process known as phase separation, which ensures spatiotemporal control over diffusion‐limited biochemical reactions. Although phase separation is a powerful mechanism to organize bioche...

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Detalles Bibliográficos
Autores principales: Alberti, Simon, Hyman, Anthony A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108435/
https://www.ncbi.nlm.nih.gov/pubmed/27554449
http://dx.doi.org/10.1002/bies.201600042