Cargando…

Retinal safety of intravitreal rtPA in healthy rats and under excitotoxic conditions

PURPOSE: Intravitreal recombinant tissue plasminogen activator (rtPA) is used off-label for the surgical management of submacular hemorrhage, a severe complication of neovascular age-related macular degeneration. rtPA is approved for coronary and cerebral thrombolysis. However, in ischemic stroke rt...

Descripción completa

Detalles Bibliográficos
Autores principales: Daruich, Alejandra, Parcq, Jérôme, Delaunay, Kimberley, Naud, Marie-Christine, Le Rouzic, Quentin, Picard, Emilie, Crisanti, Patricia, Vivien, Denis, Berdugo, Marianne, Behar-Cohen, Francine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108461/
https://www.ncbi.nlm.nih.gov/pubmed/27881907