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Retinal safety of intravitreal rtPA in healthy rats and under excitotoxic conditions

PURPOSE: Intravitreal recombinant tissue plasminogen activator (rtPA) is used off-label for the surgical management of submacular hemorrhage, a severe complication of neovascular age-related macular degeneration. rtPA is approved for coronary and cerebral thrombolysis. However, in ischemic stroke rt...

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Detalles Bibliográficos
Autores principales:	Daruich, Alejandra, Parcq, Jérôme, Delaunay, Kimberley, Naud, Marie-Christine, Le Rouzic, Quentin, Picard, Emilie, Crisanti, Patricia, Vivien, Denis, Berdugo, Marianne, Behar-Cohen, Francine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Vision 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108461/ https://www.ncbi.nlm.nih.gov/pubmed/27881907

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