Improved oral bioavailability of 20(R)-25-methoxyl-dammarane-3β, 12β, 20-triol using nanoemulsion based on phospholipid complex: design, characterization, and in vivo pharmacokinetics in rats

The aim of the study was to improve the oral absorption of the compound 25-OCH(3)-PPD with poor hydrophilicity and lipophilicity. 25-OCH(3)-PPD-phospholipid complex was prepared by solvent evaporation, then characterized by differential scanning calorimetry, scanning electron microscopy, and infrare...

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Detalles Bibliográficos
Autores principales: Zhang, Xiangrong, Zhang, Yi, Guo, Shuang, Bai, Feifei, Wu, Tong, Zhao, Yuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108498/
https://www.ncbi.nlm.nih.gov/pubmed/27877020
http://dx.doi.org/10.2147/DDDT.S114374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108498/
https://www.ncbi.nlm.nih.gov/pubmed/27877020
http://dx.doi.org/10.2147/DDDT.S114374

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