Use of ferrous iron by metallo-β-lactamases

Metallo-β-lactamases (MBLs) catalyse the hydrolysis of almost all β-lactam antibacterials including the latest generation carbapenems and are a growing worldwide clinical problem. It is proposed that MBLs employ one or two zinc ion cofactors in vivo. Isolated MBLs are reported to use transition meta...

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Detalles Bibliográficos
Autores principales: Cahill, Samuel T., Tarhonskaya, Hanna, Rydzik, Anna M., Flashman, Emily, McDonough, Michael A., Schofield, Christopher J., Brem, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108564/
https://www.ncbi.nlm.nih.gov/pubmed/27498591
http://dx.doi.org/10.1016/j.jinorgbio.2016.07.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108564/
https://www.ncbi.nlm.nih.gov/pubmed/27498591
http://dx.doi.org/10.1016/j.jinorgbio.2016.07.013

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