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Frazzled promotes growth cone attachment at the source of a Netrin gradient in the Drosophila visual system

Axon guidance is proposed to act through a combination of long- and short-range attractive and repulsive cues. The ligand-receptor pair, Netrin (Net) and Frazzled (Fra) (DCC, Deleted in Colorectal Cancer, in vertebrates), is recognized as the prototypical effector of chemoattraction, with roles in b...

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Detalles Bibliográficos
Autores principales: Akin, Orkun, Zipursky, S Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108592/
https://www.ncbi.nlm.nih.gov/pubmed/27743477
http://dx.doi.org/10.7554/eLife.20762