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Sulfonate-modified phenylboronic acid-rich nanoparticles as a novel mucoadhesive drug delivery system for vaginal administration of protein therapeutics: improved stability, mucin-dependent release and effective intravaginal placement

Effective interaction between mucoadhesive drug delivery systems and mucin is the basis of effective local placement of drugs to play its therapeutic role after mucosal administration including vaginal use, which especially requires prolonged drug presence for the treatment of gynecological infectio...

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Detalles Bibliográficos
Autores principales: Li, ChunYan, Huang, ZhiGang, Liu, ZheShuo, Ci, LiQian, Liu, ZhePeng, Liu, Yu, Yan, XueYing, Lu, WeiYue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108605/
https://www.ncbi.nlm.nih.gov/pubmed/27877038
http://dx.doi.org/10.2147/IJN.S113658