Nanomedicine strategy for optimizing delivery to outer hair cells by surface-modified poly(lactic/glycolic acid) nanoparticles with hydrophilic molecules

Targeted drug delivery to outer hair cells (OHCs) in the cochlea by nanomedicine strategies forms an effective therapeutic approach for treating hearing loss. Surface chemistry plays a deciding role in nanoparticle (NP) biodistribution, but its influence on such distribution in the cochlea remains l...

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Detalles Bibliográficos
Autores principales: Wen, Xingxing, Ding, Shan, Cai, Hui, Wang, Junyi, Wen, Lu, Yang, Fan, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108623/
https://www.ncbi.nlm.nih.gov/pubmed/27877041
http://dx.doi.org/10.2147/IJN.S116867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108623/
https://www.ncbi.nlm.nih.gov/pubmed/27877041
http://dx.doi.org/10.2147/IJN.S116867

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