Azithromycin Attenuates Pseudomonas-Induced Lung Inflammation by Targeting Bacterial Proteins Secreted in the Cultured Medium

BACKGROUND: Pseudomonas aeruginosa airway infections are a major cause of morbidity and mortality in patients with cystic fibrosis (CF). Azithromycin improves the related clinical outcomes, but its mechanisms of action remain poorly understood. We tested the hypothesis that azithromycin downregulate...

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Detalles Bibliográficos
Autores principales: Leal, Teresinha, Bergamini, Gabriella, Huaux, François, Panin, Nadtha, Noel, Sabrina, Dhooghe, Barbara, Haaf, Jeremy B., Mauri, Pierluigi, Motta, Sara, Di Silvestre, Dario, Melotti, Paola, Sorio, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108761/
https://www.ncbi.nlm.nih.gov/pubmed/27895643
http://dx.doi.org/10.3389/fimmu.2016.00499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108761/
https://www.ncbi.nlm.nih.gov/pubmed/27895643
http://dx.doi.org/10.3389/fimmu.2016.00499

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