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Evaluation of Near Infrared Dyes as Markers of P-Glycoprotein Activity in Tumors

Aim: The multidrug resistance protein 1 (MDR1; P-glycoprotein) has been associated with efflux of chemotherapeutic agents from tumor cells and with poor patient prognosis. This study evaluated the feasibility of non-invasive, non-radioactive near infrared (NIR) imaging methodology for detection of MDR...

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Detalles Bibliográficos
Autores principales: Semenenko, Inessa, Portnoy, Emma, Aboukaoud, Mohammed, Guzy, Serge, Shmuel, Miriam, Itzhak, Gal, Eyal, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108765/
https://www.ncbi.nlm.nih.gov/pubmed/27895581
http://dx.doi.org/10.3389/fphar.2016.00426