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MiR-30a-5p Overexpression May Overcome EGFR-Inhibitor Resistance through Regulating PI3K/AKT Signaling Pathway in Non-small Cell Lung Cancer Cell Lines

Lung cancer is one of the most common deadly diseases worldwide, most of which is non-small cell lung cancer (NSCLC). The epidermal growth factor receptor (EGFR) mutant NSCLCs frequently respond to the EGFR tyrosine kinase inhibitors (EGFR-TKIs) treatment, such as Gefitinib and Erlotinib, but the de...

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Detalles Bibliográficos
Autores principales: Meng, Fei, Wang, Fengfeng, Wang, Lili, Wong, S. C. Cesar, Cho, William C. S., Chan, Lawrence W. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108768/
https://www.ncbi.nlm.nih.gov/pubmed/27895663
http://dx.doi.org/10.3389/fgene.2016.00197