Cargando…

A Novel Microfluidic Cell Co-culture Platform for the Study of the Molecular Mechanisms of Parkinson's Disease and Other Synucleinopathies

Although, the precise molecular mechanisms underlying Parkinson's disease (PD) are still elusive, it is now known that spreading of alpha-synuclein (aSyn) pathology and neuroinflammation are important players in disease progression. Here, we developed a novel microfluidic cell-culture platform...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernandes, João T. S., Chutna, Oldriska, Chu, Virginia, Conde, João P., Outeiro, Tiago F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108800/
https://www.ncbi.nlm.nih.gov/pubmed/27895548
http://dx.doi.org/10.3389/fnins.2016.00511