Cargando…
A Novel Microfluidic Cell Co-culture Platform for the Study of the Molecular Mechanisms of Parkinson's Disease and Other Synucleinopathies
Although, the precise molecular mechanisms underlying Parkinson's disease (PD) are still elusive, it is now known that spreading of alpha-synuclein (aSyn) pathology and neuroinflammation are important players in disease progression. Here, we developed a novel microfluidic cell-culture platform...
Autores principales: | Fernandes, João T. S., Chutna, Oldriska, Chu, Virginia, Conde, João P., Outeiro, Tiago F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108800/ https://www.ncbi.nlm.nih.gov/pubmed/27895548 http://dx.doi.org/10.3389/fnins.2016.00511 |
Ejemplares similares
-
More than meets the eye in Parkinson’s disease and other synucleinopathies: from proteinopathy to lipidopathy
por: Flores-Leon, Manuel, et al.
Publicado: (2023) -
Drug Targeting of α-Synuclein Oligomerization in Synucleinopathies
por: Outeiro, Tiago Fleming, et al.
Publicado: (2008) -
Alpha-Synuclein: Mechanisms of Release and Pathology Progression in Synucleinopathies
por: Brás, Inês C., et al.
Publicado: (2021) -
Glucocerebrosidase Involvement in Parkinson Disease and Other Synucleinopathies
por: Almeida, Maria do Rosário
Publicado: (2012) -
Molecular chaperones and protein folding as therapeutic targets in Parkinson’s disease and other synucleinopathies
por: Ebrahimi-Fakhari, Darius, et al.
Publicado: (2013)