Amino Acid Changes at Arginine 204 of Troponin I Result in Increased Calcium Sensitivity of Force Development

Mutations in human cardiac troponin I (cTnI) have been associated with restrictive, dilated, and hypertrophic cardiomyopathies. The most commonly occurring residue on cTnI associated with familial hypertrophic cardiomyopathy (FHC) is arginine (R), which is also the most common residue at which multi...

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Detalles Bibliográficos
Autores principales: Nguyen, Susan, Siu, Rylie, Dewey, Shannamar, Cui, Ziyou, Gomes, Aldrin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108889/
https://www.ncbi.nlm.nih.gov/pubmed/27895589
http://dx.doi.org/10.3389/fphys.2016.00520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108889/
https://www.ncbi.nlm.nih.gov/pubmed/27895589
http://dx.doi.org/10.3389/fphys.2016.00520

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