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Amino Acid Changes at Arginine 204 of Troponin I Result in Increased Calcium Sensitivity of Force Development
Mutations in human cardiac troponin I (cTnI) have been associated with restrictive, dilated, and hypertrophic cardiomyopathies. The most commonly occurring residue on cTnI associated with familial hypertrophic cardiomyopathy (FHC) is arginine (R), which is also the most common residue at which multi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108889/ https://www.ncbi.nlm.nih.gov/pubmed/27895589 http://dx.doi.org/10.3389/fphys.2016.00520 |