Cyclooxygenase-1 as a Potential Therapeutic Target for Seizure Suppression: Evidences from Zebrafish Pentylenetetrazole-Seizure Model

Cyclooxygenases (COX)-1 and -2 are isoenzymes that catalyze the conversion of arachidonic acid into prostaglandins (PGs). COX-2 and PGs are rapidly increased following seizures and are known to play important roles in the neuroinflammatory process. COX-2 isoform has been predominantly explored as th...

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Detalles Bibliográficos
Autores principales: Barbalho, Patrícia Gonçalves, Carvalho, Benilton de Sá, Lopes-Cendes, Iscia, Maurer-Morelli, Claudia Vianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108920/
https://www.ncbi.nlm.nih.gov/pubmed/27895618
http://dx.doi.org/10.3389/fneur.2016.00200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108920/
https://www.ncbi.nlm.nih.gov/pubmed/27895618
http://dx.doi.org/10.3389/fneur.2016.00200

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