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Harnessing Nature’s Diversity: Discovering organophosphate bioscavenger characteristics among low molecular weight proteins

Organophosphate poisoning can occur from exposure to agricultural pesticides or chemical weapons. This exposure inhibits acetylcholinesterase resulting in increased acetylcholine levels within the synaptic cleft causing loss of muscle control, seizures, and death. Mitigating the effects of organopho...

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Detalles Bibliográficos
Autores principales: Jacob, Reed B., Michaels, Kenan C., Anderson, Cathy J., Fay, James M., Dokholyan, Nikolay V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109037/
https://www.ncbi.nlm.nih.gov/pubmed/27845442
http://dx.doi.org/10.1038/srep37175