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Sex-Specific Effects of Testosterone on the Sexually Dimorphic Transcriptome and Epigenome of Embryonic Neural Stem/Progenitor Cells

The mechanisms by which sex differences in the mammalian brain arise are poorly understood, but are influenced by a combination of underlying genetic differences and gonadal hormone exposure. Using a mouse embryonic neural stem cell (eNSC) model to understand early events contributing to sexually di...

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Detalles Bibliográficos
Autores principales: Bramble, Matthew S., Roach, Lara, Lipson, Allen, Vashist, Neerja, Eskin, Ascia, Ngun, Tuck, Gosschalk, Jason E., Klein, Steven, Barseghyan, Hayk, Arboleda, Valerie A., Vilain, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109279/
https://www.ncbi.nlm.nih.gov/pubmed/27845378
http://dx.doi.org/10.1038/srep36916