Cargando…
Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL), a Resistance Mechanism for Two Distinct Compound Classes
[Image: see text] MMV007564 is a novel antimalarial benzimidazolyl piperidine chemotype identified in cellular screens. To identify the genetic determinant of MMV007564 resistance, parasites were cultured in the presence of the compound to generate resistant lines. Whole genome sequencing revealed d...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2016
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109296/ https://www.ncbi.nlm.nih.gov/pubmed/27933786 http://dx.doi.org/10.1021/acsinfecdis.6b00025 |