Computational Drug Target Screening through Protein Interaction Profiles

The development of computational methods to discover novel drug-target interactions on a large scale is of great interest. We propose a new method for virtual screening based on protein interaction profile similarity to discover new targets for molecules, including existing drugs. We calculated Targ...

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Detalles Bibliográficos
Autores principales: Vilar, Santiago, Quezada, Elías, Uriarte, Eugenio, Costanzi, Stefano, Borges, Fernanda, Viña, Dolores, Hripcsak, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109486/
https://www.ncbi.nlm.nih.gov/pubmed/27845365
http://dx.doi.org/10.1038/srep36969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109486/
https://www.ncbi.nlm.nih.gov/pubmed/27845365
http://dx.doi.org/10.1038/srep36969

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