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Computational Drug Target Screening through Protein Interaction Profiles

The development of computational methods to discover novel drug-target interactions on a large scale is of great interest. We propose a new method for virtual screening based on protein interaction profile similarity to discover new targets for molecules, including existing drugs. We calculated Targ...

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Detalles Bibliográficos
Autores principales:	Vilar, Santiago, Quezada, Elías, Uriarte, Eugenio, Costanzi, Stefano, Borges, Fernanda, Viña, Dolores, Hripcsak, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109486/ https://www.ncbi.nlm.nih.gov/pubmed/27845365 http://dx.doi.org/10.1038/srep36969

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