Cargando…

Synthesis and bio-molecular study of (+)-N-Acetyl-α-amino acid dehydroabietylamine derivative for the selective therapy of hepatocellular carcinoma

BACKGROUND: The purpose of present work is to synthesize novel (+)-Dehydroabietylamine derivatives (DAAD) using N-acetyl-α-amino acid conjugates and determine its cytotoxic effects on hepatocellular carcinoma cells. METHODS: An analytical study was conducted to explore cytotoxic activity of DAAD on...

Descripción completa

Detalles Bibliográficos
Autores principales: Mustufa, Muhammad Ayaz, Ozen, Cigdem, Hashmi, Imran Ali, Aslam, Afshan, Baig, Jameel Ahmed, Yildiz, Gokhan, Muhammad, Shoaib, Solangi, Imam Bakhsh, ul Hasan Naqvi, Naim, Ozturk, Mehmet, Ali, Firdous Imran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109647/
https://www.ncbi.nlm.nih.gov/pubmed/27842576
http://dx.doi.org/10.1186/s12885-016-2942-5