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Synthesis and bio-molecular study of (+)-N-Acetyl-α-amino acid dehydroabietylamine derivative for the selective therapy of hepatocellular carcinoma
BACKGROUND: The purpose of present work is to synthesize novel (+)-Dehydroabietylamine derivatives (DAAD) using N-acetyl-α-amino acid conjugates and determine its cytotoxic effects on hepatocellular carcinoma cells. METHODS: An analytical study was conducted to explore cytotoxic activity of DAAD on...
Autores principales: | Mustufa, Muhammad Ayaz, Ozen, Cigdem, Hashmi, Imran Ali, Aslam, Afshan, Baig, Jameel Ahmed, Yildiz, Gokhan, Muhammad, Shoaib, Solangi, Imam Bakhsh, ul Hasan Naqvi, Naim, Ozturk, Mehmet, Ali, Firdous Imran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109647/ https://www.ncbi.nlm.nih.gov/pubmed/27842576 http://dx.doi.org/10.1186/s12885-016-2942-5 |
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