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CORALINA: a universal method for the generation of gRNA libraries for CRISPR-based screening
BACKGROUND: The bacterial CRISPR system is fast becoming the most popular genetic and epigenetic engineering tool due to its universal applicability and adaptability. The desire to deploy CRISPR-based methods in a large variety of species and contexts has created an urgent need for the development o...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109649/ https://www.ncbi.nlm.nih.gov/pubmed/27842490 http://dx.doi.org/10.1186/s12864-016-3268-z |