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Rapamycin regulates autophagy and cell adhesion in induced pluripotent stem cells

BACKGROUND: Cellular reprogramming is a stressful process, which requires cells to engulf somatic features and produce and maintain stemness machineries. Autophagy is a process to degrade unwanted proteins and is required for the derivation of induced pluripotent stem cells (iPSCs). However, the rol...

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Detalles Bibliográficos
Autores principales: Sotthibundhu, Areechun, McDonagh, Katya, von Kriegsheim, Alexander, Garcia-Munoz, Amaya, Klawiter, Agnieszka, Thompson, Kerry, Chauhan, Kapil Dev, Krawczyk, Janusz, McInerney, Veronica, Dockery, Peter, Devine, Michael J., Kunath, Tilo, Barry, Frank, O’Brien, Timothy, Shen, Sanbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109678/
https://www.ncbi.nlm.nih.gov/pubmed/27846905
http://dx.doi.org/10.1186/s13287-016-0425-x