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Rapamycin regulates autophagy and cell adhesion in induced pluripotent stem cells
BACKGROUND: Cellular reprogramming is a stressful process, which requires cells to engulf somatic features and produce and maintain stemness machineries. Autophagy is a process to degrade unwanted proteins and is required for the derivation of induced pluripotent stem cells (iPSCs). However, the rol...
Autores principales: | Sotthibundhu, Areechun, McDonagh, Katya, von Kriegsheim, Alexander, Garcia-Munoz, Amaya, Klawiter, Agnieszka, Thompson, Kerry, Chauhan, Kapil Dev, Krawczyk, Janusz, McInerney, Veronica, Dockery, Peter, Devine, Michael J., Kunath, Tilo, Barry, Frank, O’Brien, Timothy, Shen, Sanbing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109678/ https://www.ncbi.nlm.nih.gov/pubmed/27846905 http://dx.doi.org/10.1186/s13287-016-0425-x |
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