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A recombinant multi-antigen vaccine formulation containing Babesia bovis merozoite surface antigens MSA-2a(1), MSA-2b and MSA-2c elicits invasion-inhibitory antibodies and IFN-γ producing cells

BACKGROUND: Babesia bovis is a tick-transmitted protozoan hemoparasite and the causative agent of bovine babesiosis, a potential risk to more than 500 million cattle worldwide. The vaccines currently available are based on attenuated parasites, which are difficult to produce, and are only recommende...

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Detalles Bibliográficos
Autores principales: Gimenez, Alba Marina, Françoso, Katia S., Ersching, Jonatan, Icimoto, Marcelo Y., Oliveira, Vitor, Rodriguez, Anabel E., Schnittger, Leonhard, Florin-Christensen, Monica, Rodrigues, Mauricio M., Soares, Irene S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109680/
https://www.ncbi.nlm.nih.gov/pubmed/27842609
http://dx.doi.org/10.1186/s13071-016-1862-1