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Feature-based classification of human transcription factors into hypothetical sub-classes related to regulatory function

BACKGROUND: Transcription factors are key proteins in the regulation of gene transcription. An important step in this process is the opening of chromatin in order to make genomic regions available for transcription. Data on DNase I hypersensitivity has previously been used to label a subset of trans...

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Detalles Bibliográficos
Autores principales: Ehsani, Rezvan, Bahrami, Shahram, Drabløs, Finn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109715/
https://www.ncbi.nlm.nih.gov/pubmed/27842491
http://dx.doi.org/10.1186/s12859-016-1349-2