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Responses of metastatic basal cell and cutaneous squamous cell carcinomas to anti-PD1 monoclonal antibody REGN2810

BACKGROUND: Basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (CSCC) share exposure to UV light as the dominant risk factor, and these tumors therefore harbor high mutation burdens. In other malignancies, high mutation burden has been associated with clinical benefit from therapy with...

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Detalles Bibliográficos
Autores principales: Falchook, Gerald S., Leidner, Rom, Stankevich, Elizabeth, Piening, Brian, Bifulco, Carlo, Lowy, Israel, Fury, Matthew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109769/
https://www.ncbi.nlm.nih.gov/pubmed/27879972
http://dx.doi.org/10.1186/s40425-016-0176-3