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Responses of metastatic basal cell and cutaneous squamous cell carcinomas to anti-PD1 monoclonal antibody REGN2810
BACKGROUND: Basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (CSCC) share exposure to UV light as the dominant risk factor, and these tumors therefore harbor high mutation burdens. In other malignancies, high mutation burden has been associated with clinical benefit from therapy with...
Autores principales: | Falchook, Gerald S., Leidner, Rom, Stankevich, Elizabeth, Piening, Brian, Bifulco, Carlo, Lowy, Israel, Fury, Matthew G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109769/ https://www.ncbi.nlm.nih.gov/pubmed/27879972 http://dx.doi.org/10.1186/s40425-016-0176-3 |
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