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Global DNA methylation profiling uncovers distinct methylation patterns of protocadherin alpha4 in metastatic and non-metastatic rhabdomyosarcoma
BACKGROUND: Rhabdomyosarcoma (RMS), which can be classified as embryonal RMS (ERMS) and alveolar RMS (ARMS), represents the most frequent soft tissue sarcoma in the pediatric population; the latter shows greater aggressiveness and metastatic potential with respect to the former. Epigenetic alteratio...
Autores principales: | Tombolan, L., Poli, E., Martini, P., Zin, A., Millino, C., Pacchioni, B., Celegato, B., Bisogno, G., Romualdi, C., Rosolen, A., Lanfranchi, G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109816/ https://www.ncbi.nlm.nih.gov/pubmed/27842508 http://dx.doi.org/10.1186/s12885-016-2936-3 |
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