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The intriguing role of fibroblasts and c-Jun in the chemopreventive and therapeutic effect of finasteride on xenograft models of prostate cancer

In a large clinical trial, finasteride reduced the rate of low-grade prostate cancer (PCa) while increasing the incidence of high-grade cancer. Whether finasteride promotes the development of high-grade tumors remains controversial. We demonstrated the role of fibroblasts and c-Jun in chemopreventiv...

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Detalles Bibliográficos
Autores principales: Niu, Yi-Nong, Wang, Kai, Jin, Song, Fan, Dong-Dong, Wang, Ming-Shuai, Xing, Nian-Zeng, Xia, Shu-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109888/
https://www.ncbi.nlm.nih.gov/pubmed/26698232
http://dx.doi.org/10.4103/1008-682X.167714